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Online Master's in Healthcare Operational Excellence (HOPEX)

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The online Master’s in Pharmaceutical Sciences Healthcare Operational Excellence incorporates various disciplines, including operational sciences, Lean Six Sigma, automation, economics, biostatistics, and both qualitative and quantitative data analytics.

Master of Science in Healthcare Operational Excellence Program Overview

Healthcare professionals sitting in a circle during a collaborative discussion, smiling and reviewing notes in a bright meeting room.

The Master’s in Healthcare Operational Excellence program provides students with a comprehensive background in various fields including pharmacy, nursing, public health, engineering, economics, business, and allied health sciences. The program is rooted in the Pharmacy 5.0 framework and harnesses advanced technologies including Lean Six Sigma, machine learning, deep learning, artificial intelligence, and big data analysis. This graduate degree prepares students to make efficiencies in the workplace and will equip students for careers in sectors like pharmaceuticals, healthcare, and manufacturing industries.

If you have experience in business or engineering, this program could help you switch gears into the healthcare operations industry. If you’re motivated to make healthcare more efficient, the MS Pharm Sci in Healthcare Operational Excellence can give you the tools and knowledge to succeed.

Master of Science in Healthcare Operational Excellence Program Highlights

High Quality Education

The Master’s in Healthcare Operational Excellence program helps students learn how to make healthcare delivery more efficient. By studying Lean Six Sigma, process improvement methods, strategic planning, and leadership in healthcare, students become skilled at analyzing data, managing resources, and dealing with regulations. After successfully completing the program, our students optimize patient care delivery, streamline operations, and improve decision-making in healthcare management.

Learning Outcomes

Students will take courses covering topics including biostatistics, pharmacoeconomics, and pharmacy leadership, and will have the flexibility to customize a curriculum that can cater to industry-specific needs. See below for a list of the learning outcomes from this graduate level program:

  • Mastery of healthcare operations management principles, including Lean Six Sigma and process improvement methodologies.
  • Proficiency in strategic planning and organizational leadership within the healthcare sector.
  • Ability to analyze healthcare data to identify areas for improvement and implement evidence-based solutions.
  • Understanding of regulatory and compliance requirements in healthcare and their integration into operational practices.
  • Capability to lead interdisciplinary teams and drive organizational change to address complex healthcare challenges.
  • Knowledge of emerging trends and innovations in healthcare operations to improve patient outcomes and satisfaction.

Flexibility

  • Asynchronous curriculum available 24 hours a day
  • 100% online– no campus visits required
  • World-class faculty who provide personalized attention to each and every student.
  • Start-to-Graduation Support: Every student enrolled online is assigned a dedicated Student Success Coordinator providing one-on-one support. They are your partners who help you manage your time, and ensure you’re meeting degree requirements to get you to graduation.

Support from Application through Graduation

At UC, you’ll have a full support team behind you:


The online MS in Pharmaceutical Sciences : Healthcare Op Excellence is 30 credit hours and can be completed in 2 years.

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Students must complete all of the following
Course Title/Description Credit
PADM7010

Medication Use System Analyses and Improvement

Medication use system analysis, system improvement, pharmacy automation, quality assurance, utilization of pharmacy staff, facility design, and lean process.

2
PCEU7010

Biostatistics & Research Methods

The course begins with basic statistical concepts, introduces essential descriptive and inferential statistical tests, demonstrates some data analysis tools and collection instruments, then discusses common research methodology for pharmaceutical and cosmetic sciences.  Students will learn how to use statistics and research designs to evaluate scientific evidence to make individual and population-based decisions.  Students will conduct some simple statistical analysis based on given data sets and interpret the results, as well review clinical research literature. 

3
PADM7050

Pharmacoeconomics & Decision Analytical Modeling 

This course is designed to provide an understanding of the theory and application of economic evaluation methods used in healthcare decision-making. Various methods such as cost-effectiveness analysis, cost-utility analysis, cost-minimization analysis, and cost-benefit analysis will be discussed to evaluate healthcare services, pharmaceuticals, and medical device products. Additionally, techniques to measure costs and outcomes will be discussed in detail along with assigning the monetary value to outcomes. Different types of models such as decision trees and Markov models will be taught. Students will have a chance to conduct independent group projects using a decision-analytic software package by which they will be able to conduct a cost-effectiveness analysis to compare different therapeutic options.

3
PCEU7050

Ethics in Scientific Research- Pharmacy

Students will learn about the various ethical and moral issues that are often encountered in scientific research including ways to identify and analyze them in the practice of research. The course is designed as an option to meet the NIH and NSF requirements for training in RCR (Responsible conduct of research).   Topics to be covered include:  RCR principles and guidelines, mentorship, collaborative research, conflict of interests, authorship and plagiarism, intellectual property and data handling, research involving human and animal subjects, scientific integrity and misconduct and social responsibility.

1
PHID
Healthcare Operational Excellence Capstone

Students will take this course in the last semester. This course will be offered every semester.
3
Students must complete the listed courses for 9 credit hours
Course Title/Description Credit
PADM7110

Lean Six Sigma I
Introduction to Lean Six Sigma

To become more competitive, industry is looking for individuals that understand how to both problems solve and eliminate waste within an organization. This course provides students with the tools, techniques and methodologies that will enable them to lead LSS projects in their organization. Students will learn how to apply the problem-solving framework for improving processes – Define, Measure, Analyze, Improve and Control (DMAIC), develop knowledge of using the tools and methodologies for streamlining end-to-end processes by eliminating non-value-added activities and reduce variation in processes to improve quality and reduce rework. The course will utilize lectures and various case studies to demonstrate the understanding and application of these principles.

3
PADM7120

Lean Six Sigma II
Management in Healthcare 

In this course, students will gain knowledge in the application of quality improvement methodology in both manufacturing and service environments related to healthcare. Emphasis will be placed on philosophical approaches to quality improvement and quantitative methods of quality control. The following topics will be included: Corporate Quality Programs, Applications for Quality Improvement, Measurement System Analysis, Statistical Process Control, Experimental Design, Root Cause Analysis, and Design for Quality. Students will be expected to use MS Office, especially Excel, and Minitab in this course to complete assignments and the final project.

3
PADM7130

Lean Six Sigma III
Standard Work and Sustainability 

This course focuses on the essential elements of a Lean Management System, providing students with the tools and techniques and thinking way to effectively communicate and control plans, processes, activities, deliverables, responsibilities, and results through visual management. Students will learn to design and utilize visual displays that share information and workplace standards and develop and apply visual controls to make key performance indicators visible across various areas including safety, delivery, quality, cost, and morale. Additionally, the course covers strategies for workplace organization and standardization, effective performance review, and various problem-solving techniques to identify, analyze, and resolve issues efficiently - called the 4 plays. By the end of the course, students will be equipped with the skills and knowledge to lead Lean Six Sigma projects and drive continuous improvement in their organizations.

3
Students must complete at least 9 credit hours to meet the 30-credit hour requirement
Course Title/Description Credit
CS6101

Introduction to Applied Artificial Intelligence and Machine Learning Tools*

This course is designed for professionals who already have basic knowledge of Python programming and basic algorithms, but are looking to refresh their knowledge and expand their hands-on skills on recent Machine Learning tools. Students will be introduced to popular AI techniques conceptually and will learn to evaluate the performance of the algorithms themselves, taking advantage of the latest tools available. Furthermore, they will learn how to adapt and customize the algorithms on new problems reviewing examples. Supervised learning techniques (regression, classification, neural networks and SVM), unsupervised learning techniques (clustering, SOM, PCA) and anomaly detection algorithms will be covered.   

*By Permission Only

3
MECH6078

Industrial big data includes all types of data generated from industry applications consisting of machine operation, manufacturing process and maintenance events, etc. In today’s competitive business environments, companies have urgent needs to use advanced analytical tools to manage their industrial data to gain more insights of their operations. This course will introduce students to advanced technologies—such as advanced signal processing, pattern recognition & machine learning and predictive analytics—that ultimately enable the conversion of industrial big data into actionable information that can be used to improve the design, the productivity and the efficiency of manufacturing operations.

3
PHLD8010

Leading Quality Management in Pharmacy

This course present students  with a comprehensive overview of quality management principles, concepts and tools used in healthcare with a special emphasis in pharmacy practice.  Through an analysis of pharmacy -related cases, students will have the opportunity to evaluate the relationship between leadership principles and quality  improvement. Topics include quality performance measurement, culture of quality, techniques for quality  leadership, patient engagement in quality  and the use of technology in quality improvement.

3
PHLD8040

Medication Use System Management

This course covers the elements of the medication use system and will assist students in developing skills to assume a leadership role in devising and implementing process improvements of use of health care technologies (electronic health record, bar codes, robotics, smart devices) in the medication system along with HIT standards for interface and integration, and mobile health technologies.  Students will gain an understanding of personal health records and models of community and regional information networks. Course content will include activities in workflow process mapping and workflow redesign, project management, and processes for documentation and coding.

3
PHLD8070

Accounting and Financial Decision- Making for Pharmacy Leaders

This course covers selected financial and managerial aspects of healthcare financial management, specifically designed for Pharmacists. It provides a broad introduction to key concepts, issues, tools, and vocabulary useful for managers, department heads, and owners. There are three main topic areas covered in the course: financial accounting; finance; and managerial accounting. The focus is on the understanding and application of the accounting information in healthcare with emphasis on addressing use within the pharmacy.

3
PHLD8050

The Healthcare MarketPlace- Pharmacy Economics

This course provides an overview of economics and  marketplace topics related to pharmacy, with particular emphasis on topics relevant to the pharmaceutical industry and health benefit payment models.  This course will provide an introduction to the fundamentals of Pharmacoeconomics and outcomes research. Pharmacy business aspects of pharmaceutical  regulation and pricing, contracts and purchasing  models, group purchasing organizations, MTM reimbursement, specialty pharmacy, and value based clinical and financial models for future health care delivery will all be addressed in the course  content.  Innovation and marketing will also be included with cases and application activities.

3
Prerequisites
  • A U.S. bachelors degree from a regionally accredited college or university or an equivalent degree from a foreign country
  • A minimum 3.0 cumulative GPA
  • For international students, a Test of English as a Foreign Language (TOEFL) of at least 90 (internet-based) or 235 (computer-based), or a Duolingo English Test of at least 110 is accepted
    • Transcripts must be submitted for evaluation to an agency recognized by the National Association of Credential Evaluating Services (NACES: www.naces.org)

Complete the online application and submit the application fee.

Standard Application Fees:

  • $65.00 for domestic applicants to most degree programs
  • $70.00 for international applicants to most degree programs
  • $20.00 for domestic applicants to Graduate Certificates
  • $25.00 for international applicants to Graduate Certificates
  • Application fees are waived for Summer 2026 applications submitted by March 1st, 2026
  • Application fees are waived for Fall 2026 applications submitted by July 1st, 2026
  • Fee waivers are automatically applied for applicants who: 
    • are currently serving in the US armed forces
    • are veterans of the US armed forces

All applicants are required to upload unofficial transcripts during the application process, showing all undergraduate and graduate course work completed, including degrees granted and dates of conferral.

Official transcripts are not required until the student has received and accepted an offer of admission from the university. Once the offer has been confirmed, the student must submit official transcripts.

Students who have received degrees from the University of Cincinnati do not need to submit official paper copies of their UC transcripts.

Transcripts can be submitted electronically or by mail. To see if your transcript(s) can be ordered electronically, visit the links below and search for your previous school(s).

If you do not see your past school(s) listed on either site, please contact the school(s) directly. Then, mail your sealed, unopened, official transcripts to:

Please mail sealed, unopened, official transcripts to:

University of Cincinnati
Office of Admissions
PO Box 210091
Cincinnati, Ohio 45221-0091

Two letters of reference are required.

  • References should come from individuals who can attest to your academic and professional skills. Letters of recommendation from family, friends, current students, politicians, or clergy are not accepted.

Provide a few paragraphs on why you plan to pursue this program and how you plan to use this degree in the future.

A professional and current resume or curriculum vitae.

Students living abroad are eligible to pursue this program, but will not be qualified for F-1 Visa status in this online program 

Applicants with college coursework completed outside the United States are required to provide a course-by-course foreign credential evaluation for each college or university you attended outside the United States. This evaluation must be obtained from a service listed on the NACES member website. 

Students who are not permanent residents of the United States or earned a degree from an institution where English was not the language of instruction must complete a Test of English as a Foreign Language (TOEFL) test when applying. The minimum score required for admission is 90 (internet-based test). If you have a bachelor's degree or higher from a United States university, this requirement will be waived. IELTS score of 7 or higher is preferred or a Duolingo score of 110 or higher is also acceptable.

Transcripts must also be submitted for evaluation to an agency recognized by the National Association of Credential Evaluating Services (NACES; www.naces.org). Reference the Official Transcript Submission Policy for Enrollment for more information.

At the University of Cincinnati, we offer multiple start dates to accommodate your schedule. 
Term Application Deadline Classes Start

Summer 2026

Fall 2026

Spring 2027

April 30, 2026

August 15, 2026

December 15, 2026

May 11, 2026

August 24, 2026

January 11, 2027

The University of Cincinnati's online course fees differ depending on the program. On average, students will accrue fewer fees than students attending on-campus classes.

The one fee applied across all UC Online programs is the distance learning fee. Students living outside the state of Ohio must also pay an additional “non-resident” fee to enroll in courses at UC Online. This fee is lower than the out-of-state fee for traditional on-campus programs.

To view tuition information and program costs, visit the Online Program Fees page.

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